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Wednesday August 29, 2001
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FAT MAY REPLACE EMBRYONIC TISSUE AS PRIME SOURCE FOR STEM CELL RESEARCH
LOS ANGELES, August 29, 2001 (LSN.ca) - Human fat, collected by liposuction, shows promise of providing a plentiful source of replacement cells for a variety of medical treatments. This would possibly eliminating the controversial use of embryonic stem cells say researchers from two American Universities. The UCLA and University of Pittsburgh researchers have isolated stem cells -- cells with the potential to become virtually any type of tissue -- from fat and converted them into bone, cartilage and muscle.
"This could take the air right out of the debate about embryonic stem cells," said Dr.Mark Hedrick of UCLA, the lead author of the study. The newly identified cells have so great a potential "it makes it hard to argue that we should use embryonic cells," he said.
The best adult source of such cells now is bone marrow, but recovering the cells requires drilling a hole directly into the bone, which remains painful for weeks after the procedure and the yield is small. Liposuction of fat is relatively painless and the procedure produces a thousand times as many stem cells as can be obtained from bone marrow. Also, using oneâs own fat would eliminate the problem of rejection of implanted cells.
Tissue experiments are currently being performed on animals and it will take about five years before the first clinical trials could be conducted in humans.
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